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Adaptogens

Ashwagandha, rhodiola, and other adaptogenic compounds for stress resilience, cortisol, sleep, and cognitive performance.

Evidence is mixed

Ashwagandha has the strongest RCT evidence for cortisol reduction and sleep quality (Chandrasekhar et al., 2012; Langade et al., 2019). Rhodiola evidence for fatigue is promising but studies are small. Marketing claims substantially outrun the controlled trial record for most other adaptogens.

Evidence base

Min quality:
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