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Probiotics
Gut microbiome interventions — probiotic strains, fermented foods, and prebiotic fiber for mood, immunity, and digestion.
Evidence is mixed
Gut-brain axis effects are real but highly strain-specific — evidence for Lactobacillus helveticus R0052 + Bifidobacterium longum R0175 on anxiety is the strongest human RCT signal. Most commercial probiotic blends have not been tested at specific doses in RCTs. Effects on digestion are more robust than effects on mood or cognition.
Evidence base
Min quality:
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