Meta-analysisTop journalWikiHigh evidence score
The Common Neural Basis of Autobiographical Memory, Prospection, Navigation, Theory of Mind, and the Default Mode: A Quantitative Meta-analysis
R. Nathan Spreng, Raymond A. Mar, Alice S. N. Kim · Journal of Cognitive Neuroscience · 2008 · 2,189 citations
This meta-analysis of 24 neuroimaging studies provides quantitative evidence that remembering your past, imagining your future, navigating space, understanding others' minds, and daydreaming all rely on a single core brain network — meaning that improving one of these abilities (e.g., memory) may transfer to others (e.g., empathy or navigation), which has direct implications for designing personal experiments that target multiple cognitive skills simultaneously.
Read the breakdown →Systematic ReviewWikiHigh evidence score
Case Detection, Diagnosis, and Treatment of Patients with Primary Aldosteronism: An Endocrine Society Clinical Practice Guideline
John W. Funder, Robert M. Carey, Carlos Fardella +5 more · The Journal of Clinical Endocrinology & Metabolism · 2008 · 1,548 citations
This clinical practice guideline synthesises the best available evidence to recommend that hypertensive patients with certain risk factors (including resistant hypertension, hypokalemia, or an adrenal mass) should be systematically screened for primary aldosteronism using the aldosterone-renin ratio, and that confirmed cases should undergo subtype testing (adrenal CT followed by adrenal venous sampling) to distinguish unilateral from bilateral disease, because the two forms require fundamentally different treatments (surgery vs. medication) with dramatically different outcomes.
Read the breakdown →Systematic ReviewWikiHigh evidence score
Religion, Spirituality, and Health: The Research and Clinical Implications
Harold G. Koenig · ISRN Psychiatry · 2012 · 2,238 citations
This systematic review found consistent evidence that engaging in religious or spiritual practices is associated with better mental health, healthier behaviors, and improved physical health outcomes, suggesting that incorporating such practices could be a beneficial self-experiment for overall well-being.
Read the breakdown →Meta-analysisTop journalWikiHigh evidence score
Association Between Screen Media Use and Academic Performance Among Children and Adolescents
Mireia Adelantado‐Renau, Diego Moliner‐Urdiales, Iván Cavero‐Redondo +3 more · JAMA Pediatrics · 2019 · 289 citations
This meta-analysis of 58 studies involving 480,479 participants found that overall screen time was not significantly associated with academic performance, but specific screen activities—television viewing and video game playing—showed small negative associations with composite academic scores, language, and mathematics, with effects varying by age group.
Read the breakdown →Systematic ReviewWikiHigh evidence score
Canadian 24-Hour Movement Guidelines for the Early Years (0–4 years): An Integration of Physical Activity, Sedentary Behaviour, and Sleep
Mark S. Tremblay, Jean‐Philippe Chaput, Kristi B. Adamo +23 more · BMC Public Health · 2017 · 644 citations
This systematic review and guideline development process integrated evidence from four systematic reviews and compositional data analyses to produce the first integrated 24-hour movement behaviour guidelines for children aged 0–4 years, recommending specific daily combinations of physical activity, sedentary behaviour (including screen time), and sleep that are associated with better health outcomes across adiposity, motor development, cognitive development, and psychosocial health.
Read the breakdown →Meta-analysisHigh evidence score
Recovery from work‐related effort: A meta‐analysis
Andrew Bennett, Arnold B. Bakker, James G. Field · Journal of Organizational Behavior · 2017 · 378 citations
Summary This meta‐analytic study examines the antecedents and outcomes of four recovery experiences: psychological detachment, relaxation, mastery, and control. Using 299 effect sizes from 54 independent samples ( N = 26,592), we extend theory by integrating recovery experiences into the challenge–hindrance framework, creating a more comprehensive understanding of how both after‐work recovery and work characteristics collectively relate to well‐being. The results of meta‐analytic path estimates indicate that challenge demands have stronger negative relationships with psychological detachment, relaxation, and control recovery experiences than hindrance demands, and job resources have positive relationships with relaxation, mastery, and control recovery experiences. Psychological detachment after work has a stronger negative relationship with fatigue than relaxation or control experiences, whereas control experiences after work have a stronger positive relationship with vigor than detachment or relaxation experiences. Additionally, a temporally driven model with recovery experiences as a partial mediator explains up to 62% more variance in outcomes (Δ R 2 = .12) beyond work characteristics models, implying that both work characteristics and after‐work recovery play an important role in determining employee well‐being.
Meta-analysisWikiHigh evidence score
Benefits and Pitfalls of Multimedia and Interactive Features in Technology-Enhanced Storybooks
Zsófia K. Takács, Elise K. Swart, Adriana G. Bus · Review of Educational Research · 2015 · 373 citations
Technology-enhanced storybooks (e.g., e-books with animations, sound effects, and interactive games) produce a small but reliable improvement in young children's story comprehension and vocabulary compared to traditional reading, but only when they include multimedia features (animations, music, sound effects) — interactive features like hotspots, games, and built-in dictionaries actually harm learning, especially for children from less stimulating home environments.
Read the breakdown →Systematic ReviewWikiHigh evidence score
A collaborative approach to adopting/adapting guidelines - The Australian 24-Hour Movement Guidelines for the early years (Birth to 5 years): an integration of physical activity, sedentary behavior, and sleep
Anthony D. Okely, Davina Ghersi, Kylie D. Hesketh +24 more · BMC Public Health · 2017 · 443 citations
This paper describes how Australia adapted Canada's 24-hour movement guidelines for children aged 0–5 years using a structured, transparent process (GRADE-ADOLOPMENT), adopting nearly all Canadian recommendations with only minor wording changes, which saved time and money compared to developing guidelines from scratch.
Read the breakdown →Meta-analysisWikiHigh evidence score
A proposed panel of biomarkers of healthy ageing
José Lara, Rachel Cooper, Jack Nissan +6 more · BMC Medicine · 2015 · 234 citations
This meta-analysis and expert consensus identified a core panel of 15–20 biomarkers across five domains (physical capability, cognitive function, physiological function, endocrine function, and immune function) that reliably decline with age, providing a standardised toolkit for researchers and self-experimenters to measure how fast their body is ageing and whether interventions slow that decline.
Read the breakdown →RCTTop journalWikiHigh evidence score
Understanding and misunderstanding randomized controlled trials
Angus Deaton, Nancy Cartwright · Social Science & Medicine · 2017 · 1,799 citations
This paper argues that while Randomized Controlled Trials (RCTs) are valuable, they are often over-trusted and misunderstood, especially regarding their ability to equalize groups, provide precise estimates, or guarantee generalizability, meaning self-experimenters should be highly critical of RCT findings and thoughtfully design their own experiments to understand *why* something works, not just *if* it works for a specific group.
Read the breakdown →Systematic ReviewWikiHigh evidence score
Practice guideline: Treatment for insomnia and disrupted sleep behavior in children and adolescents with autism spectrum disorder
Ashura Buckley, Deborah Hirtz, Maryam Oskoui +23 more · Neurology · 2020 · 212 citations
This systematic review found that behavioral sleep interventions (sleep hygiene education, parent training) should be the first-line treatment for sleep disturbances in children with autism spectrum disorder, and if those fail, pharmaceutical-grade melatonin (starting low, ~0.5–1 mg) is the only medication with sufficient evidence to recommend — but long-term safety data beyond 6–12 months are lacking, and weighted blankets or specialized mattresses have no evidence supporting routine use.
Read the breakdown →Meta-analysisWikiHigh evidence score
Virtual reality improves emotional but not cognitive empathy: A meta-analysis.
Alison Jane Martingano, Fernanda Hererra, Sara Konrath · Technology Mind and Behavior · 2021 · 164 citations
Virtual reality experiences reliably boost emotional empathy (feeling *with* someone) by a small-to-moderate amount, but they do not improve cognitive empathy (understanding someone's perspective), and VR is no more effective than simply reading a story or imagining someone else's experience — meaning you can get the same empathy boost from a book as from a $400 headset.
Read the breakdown →RCTTop journalWikiHigh evidence score
A gender-sensitised weight loss and healthy living programme for overweight and obese men delivered by Scottish Premier League football clubs (FFIT): a pragmatic randomised controlled trial
Kate Hunt, Sally Wyke, Cindy M. Gray +12 more · The Lancet · 2014 · 391 citations
A 12-week weight loss programme delivered in professional football stadiums helped overweight and obese men lose an average of 4.94 kg more than men who received only a booklet, with effects sustained at 12 months — showing that men will engage with and benefit from weight loss programmes when the setting and delivery are tailored to them.
Read the breakdown →RCTLeading journalWikiHigh evidence score
Improving Adherence and Clinical Outcomes in Self-Guided Internet Treatment for Anxiety and Depression: Randomised Controlled Trial
Nickolai Titov, Blake F. Dear, Luke Johnston +6 more · PLoS ONE · 2013 · 377 citations
Adding automated reminder and encouragement emails to an 8-week self-guided online treatment for anxiety and depression nearly doubled course completion rates (58% vs. 35%) and produced significantly larger reductions in depression and anxiety symptoms compared to the same treatment without emails, with effect sizes in the moderate-to-large range (Cohen's d = 0.52–0.74).
Read the breakdown →Meta-analysisHigh evidence score
Gender Imbalance in Instructional Dynamic Versus Static Visualizations: a Meta-analysis
Juan C. Castro-Alonso, Mona Wong, Olusola Adesope +2 more · Educational Psychology Review · 2019 · 100 citations
RCTLeading journalWikiHigh evidence score
A Multisite Randomized Trial of Portable Sleep Studies and Positive Airway Pressure Autotitration Versus Laboratory-Based Polysomnography for the Diagnosis and Treatment of Obstructive Sleep Apnea: The HomePAP Study
Carol L. Rosen, Dennis Auckley, Ruth M. Benca +6 more · SLEEP · 2012 · 364 citations
A home-based approach using portable sleep monitors and automatic CPAP machines was as effective as in-laboratory sleep studies for diagnosing and treating moderate-to-severe obstructive sleep apnea, and led to patients using their CPAP machines for about one hour more per night after three months.
Read the breakdown →RCTLeading journalWikiHigh evidence score
Psychological impacts of “screen time” and “green time” for children and adolescents: A systematic scoping review
Tassia K. Oswald, Alice Rumbold, Sophie G. E. Kedzior +1 more · PLoS ONE · 2020 · 340 citations
Technological developments in recent decades have increased young people's engagement with screen-based technologies (screen time), and a reduction in young people's contact with nature (green time) has been observed concurrently. This combination of high screen time and low green time may affect mental health and well-being. The aim of this systematic scoping review was to collate evidence assessing associations between screen time, green time, and psychological outcomes (including mental health, cognitive functioning, and academic achievement) for young children (<5 years), schoolchildren (5-11 years), early adolescents (12-14 years), and older adolescents (15-18 years). Original quantitative studies were identified in four databases (PubMed, PsycInfo, Scopus, Embase), resulting in 186 eligible studies. A third of included studies were undertaken in Europe and almost as many in the United States. The majority of studies were cross-sectional (62%). In general, high levels of screen time appeared to be associated with unfavourable psychological outcomes while green time appeared to be associated with favourable psychological outcomes. The ways screen time and green time were conceptualised and measured were highly heterogeneous, limiting the ability to synthesise the literature. The preponderance of cross-sectional studies with broadly similar findings, despite heterogeneous exposure measures, suggested results were not artefacts. However, additional high-quality longitudinal studies and randomised controlled trials are needed to make a compelling case for causal relationships. Different developmental stages appeared to shape which exposures and outcomes were salient. Young people from low socioeconomic backgrounds may be disproportionately affected by high screen time and low green time. Future research should distinguish between passive and interactive screen activities, and incidental versus purposive exposure to nature. Few studies considered screen time and green time together, and possible reciprocal psychological effects. However, there is preliminary evidence that green time could buffer consequences of high screen time, therefore nature may be an under-utilised public health resource for youth psychological well-being in a high-tech era.
Read the breakdown →Meta-analysisWikiHigh evidence score
Trends in Research on Writing as a Learning Activity
Peter Klein, Pietro Boscolo · Journal of Writing Research · 2016 · 212 citations
Writing reliably improves learning across subjects, but the effect depends on *how* you write — reflective, explanatory writing that forces you to reorganise knowledge works far better than simple note-taking or summarising, and the gains are roughly equivalent to raising test scores by 0.3–0.5 standard deviations (a medium effect).
Read the breakdown →Systematic ReviewWikiHigh evidence score
Health promoting schools and health promotion in schools: two systematic reviews.
D Lister-Sharp, Susan Chapman, Sarah Stewart‐Brown +1 more · Health Technology Assessment · 1999 · 382 citations
This systematic review of 29 studies found that school-based health promotion programmes can produce small but measurable improvements in student health behaviours (e.g., 5–15% reductions in smoking initiation and 3–8% increases in physical activity), but effects vary widely by programme type, duration, and implementation quality — and most studies lacked long-term follow-up, so lasting behaviour change remains unproven.
Read the breakdown →Systematic ReviewLeading journalWikiHigh evidence score
Sleep and its relation to cognition and behaviour in preschool‐aged children of the general population: a systematic review
Eve Reynaud, Marie‐Françoise Vecchierini, Barbara Heude +2 more · Journal of Sleep Research · 2017 · 147 citations
In preschool-aged children (3–5 years), getting more sleep and better-quality sleep is associated with small but consistent improvements in behaviour and cognitive performance, but the effects are modest and require large sample sizes to detect, meaning individual children may not notice dramatic changes from a single night's improvement.
Read the breakdown →RCTTop journalWikiHigh evidence score
Helmet therapy in infants with positional skull deformation: randomised controlled trial
Roelof Van Wijk, Leo A. van Vlimmeren, Karin Groothuis‐Oudshoorn +3 more · BMJ · 2014 · 220 citations
Helmet therapy for moderate-to-severe positional skull deformation in infants aged 5–6 months produced no meaningful improvement in skull shape compared to doing nothing, with full recovery rates of 26% (helmet) vs 23% (natural course) — a statistically indistinguishable difference — while causing side effects in every treated infant.
Read the breakdown →RCTTop journalWikiHigh evidence score
Effect of Sleep Extension on Objectively Assessed Energy Intake Among Adults With Overweight in Real-life Settings
Esra Tasali, Kristen Wroblewski, Eva Kahn +2 more · JAMA Internal Medicine · 2022 · 146 citations
Extending sleep by about 1.2 hours per night in adults who habitually slept less than 6.5 hours led to an average reduction of 270 calories per day in energy intake, with no change in energy expenditure, resulting in weight loss — suggesting that improving sleep duration alone can shift energy balance in a direction that supports weight management.
Read the breakdown →StudyTop journalWikiModerate
Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission
Gill Livingston, Jonathan Huntley, Kathy Liu +24 more · The Lancet · 2024 · 2,694 citations
This 2024 update from the Lancet Commission identifies 14 modifiable risk factors that together account for approximately 45% of dementia cases worldwide, meaning nearly half of all dementia could theoretically be prevented or delayed through addressing these factors across the lifespan.
Read the breakdown →RCTTop journalWikiHigh evidence score
Telephone-Based Cognitive Behavioral Therapy for Insomnia in Perimenopausal and Postmenopausal Women With Vasomotor Symptoms
Susan M. McCurry, Katherine A. Guthrie, Charles M. Morin +13 more · JAMA Internal Medicine · 2016 · 178 citations
Six telephone-delivered sessions of cognitive behavioral therapy for insomnia (CBT-I) over 8 weeks produced a 5.2-point greater reduction in insomnia severity compared to a menopause education control, with 84% of CBT-I participants achieving no-insomnia status by 24 weeks, and the benefits persisted even though hot flash frequency itself did not change.
Read the breakdown →StudyTop journalModerate
The psychological drivers of misinformation belief and its resistance to correction
Ullrich K. H. Ecker, Stephan Lewandowsky, John Cook +6 more · Nature Reviews Psychology · 2022 · 1,230 citations
ObservationalLeading journalModerate
Insomnia with Objective Short Sleep Duration is Associated with a High Risk for Hypertension
Alexandros N. Vgontzas, Duanping Liao, Edward O. Bixler +2 more · SLEEP · 2009 · 752 citations
STUDY OBJECTIVES: To examine the joint effect of insomnia and objective short sleep duration on hypertension risk. DESIGN: Representative cross-sectional study. SETTING: Sleep laboratory. PARTICIPANTS: 1,741 men and women randomly selected from central Pennsylvania. INTERVENTIONS: None. MEASUREMENTS: Insomnia was defined by a complaint of insomnia with a duration > or = 1 year, while poor sleep was defined as a complaint of difficulty falling asleep, staying asleep, or early final awakening. Polysomnographic sleep duration was classified into 3 categories: > or = 6 h sleep (top 50% of the sample); 5-6 h (approximately the third quartile of the sample); and < or = 5 h (approximately the bottom quartile of the sample). Hypertension was defined based either on blood pressure measures or treatment. We controlled for age, race, sex, body mass index, diabetes, smoking, alcohol use, depression, sleep disordered breathing (SDB), and sampling weight. RESULTS: Compared to the normal sleeping and > 6 h sleep duration group, the highest risk of hypertension was in insomnia with < 5 h sleep duration group (OR [95% CI] 5.1 [2.2, 11.8]), and the second highest in insomnia who slept 5-6 hours (OR 3.5 [1.6, 7.9] P < 0.01). The risk for hypertension was significantly higher, but of lesser magnitude, in poor sleepers with short sleep duration. CONCLUSIONS: Insomnia with short sleep duration is associated with increased risk of hypertension, to a degree comparable to that of other common sleep disorders, e.g., SDB. Objective sleep duration may predict the severity of chronic insomnia a prevalent condition whose medical impact has been apparently underestimated.
StudyWikiModerate
Human resource management in the age of generative artificial intelligence: Perspectives and research directions on ChatGPT
Pawan Budhwar, Soumyadeb Chowdhury, Geoffrey Wood +20 more · Human Resource Management Journal · 2023 · 722 citations
This perspectives editorial synthesises existing literature to argue that generative AI (like ChatGPT) will fundamentally reshape human resource management (HRM) across recruitment, performance management, employee well-being, and ethical compliance, but the evidence base is almost entirely theoretical — no controlled experiments exist yet, so anyone running a self-experiment on using generative AI for HR tasks must treat all claims as hypotheses, not proven effects.
Read the breakdown →ObservationalWikiModerate
Economic Analysis of Social Interactions
Charles F. Manski · The Journal of Economic Perspectives · 2000 · 2,083 citations
Social interactions—how your behaviour is influenced by the people around you—are extremely difficult to study using observational data because many different causal mechanisms can produce the same observed patterns, meaning that without controlled experiments or subjective data on expectations, you cannot reliably tell whether your friends' actions caused your behaviour or whether you simply chose friends who already behaved like you.
Read the breakdown →StudyTop journalModerate
Mind the Hype: A Critical Evaluation and Prescriptive Agenda for Research on Mindfulness and Meditation
Nicholas T. Van Dam, Marieke K. van Vugt, David R. Vago +12 more · Perspectives on Psychological Science · 2017 · 1,483 citations
During the past two decades, mindfulness meditation has gone from being a fringe topic of scientific investigation to being an occasional replacement for psychotherapy, tool of corporate well-being, widely implemented educational practice, and "key to building more resilient soldiers." Yet the mindfulness movement and empirical evidence supporting it have not gone without criticism. Misinformation and poor methodology associated with past studies of mindfulness may lead public consumers to be harmed, misled, and disappointed. Addressing such concerns, the present article discusses the difficulties of defining mindfulness, delineates the proper scope of research into mindfulness practices, and explicates crucial methodological issues for interpreting results from investigations of mindfulness. For doing so, the authors draw on their diverse areas of expertise to review the present state of mindfulness research, comprehensively summarizing what we do and do not know, while providing a prescriptive agenda for contemplative science, with a particular focus on assessment, mindfulness training, possible adverse effects, and intersection with brain imaging. Our goals are to inform interested scientists, the news media, and the public, to minimize harm, curb poor research practices, and staunch the flow of misinformation about the benefits, costs, and future prospects of mindfulness meditation.
StudyModerate
ESPEN guideline on clinical nutrition and hydration in geriatrics
Dorothee Volkert, Anne Marie Beck, Tommy Cederholm +11 more · Clinical Nutrition · 2018 · 1,357 citations
StudyModerate
Advances in Social Media Research: Past, Present and Future
Kawaljeet Kaur Kapoor, Kuttimani Tamilmani, Nripendra P. Rana +3 more · Information Systems Frontiers · 2017 · 1,254 citations
Social media comprises communication websites that facilitate relationship forming between users from diverse backgrounds, resulting in a rich social structure. User generated content encourages inquiry and decision-making. Given the relevance of social media to various stakeholders, it has received significant attention from researchers of various fields, including information systems. There exists no comprehensive review that integrates and synthesises the findings of literature on social media. This study discusses the findings of 132 papers (in selected IS journals) on social media and social networking published between 1997 and 2017. Most papers reviewed here examine the behavioural side of social media, investigate the aspect of reviews and recommendations, and study its integration for organizational purposes. Furthermore, many studies have investigated the viability of online communities/social media as a marketing medium, while others have explored various aspects of social media, including the risks associated with its use, the value that it creates, and the negative stigma attached to it within workplaces. The use of social media for information sharing during critical events as well as for seeking and/or rendering help has also been investigated in prior research. Other contexts include political and public administration, and the comparison between traditional and social media. Overall, our study identifies multiple emergent themes in the existing corpus, thereby furthering our understanding of advances in social media research. The integrated view of the extant literature that our study presents can help avoid duplication by future researchers, whilst offering fruitful lines of enquiry to help shape research for this emerging field.
StudyModerate
The impact of stress on students in secondary school and higher education
Michaela C. Pascoe, Sarah Hetrick, Alexandra Parker · International Journal of Adolescence and Youth · 2019 · 1,204 citations
Students in secondary and tertiary education settings face a wide range of ongoing stressors related to academic demands. Previous research indicates that academic-related stress can reduce academic achievement, decrease motivation and increase the risk of school dropout. The longer-term impacts, which include reduced likelihood of sustainable employment, cost Governments billions of dollars each year. This narrative review presents the most recent research concerning the impact of academic-related stress, including discussion of the impact on students’ learning capacity and academic performance, mental health problems, such as depression and anxiety, sleep disturbances and substance use.
StudyTop journalModerate
Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms
Samuel E. Jones, Jacqueline M. Lane, Andrew R. Wood +29 more · Nature Communications · 2019 · 719 citations
Being a morning person is a behavioural indicator of a person's underlying circadian rhythm. Using genome-wide data from 697,828 UK Biobank and 23andMe participants we increase the number of genetic loci associated with being a morning person from 24 to 351. Using data from 85,760 individuals with activity-monitor derived measures of sleep timing we find that the chronotype loci associate with sleep timing: the mean sleep timing of the 5% of individuals carrying the most morningness alleles is 25 min earlier than the 5% carrying the fewest. The loci are enriched for genes involved in circadian regulation, cAMP, glutamate and insulin signalling pathways, and those expressed in the retina, hindbrain, hypothalamus, and pituitary. Using Mendelian Randomisation, we show that being a morning person is causally associated with better mental health but does not affect BMI or risk of Type 2 diabetes. This study offers insights into circadian biology and its links to disease in humans.
StudyTop journalModerate
The Ease of Language Understanding (ELU) model: theoretical, empirical, and clinical advances
Jerker Rönnberg, Thomas Lunner, Adriana A. Zekveld +8 more · Frontiers in Systems Neuroscience · 2013 · 962 citations
Working memory is important for online language processing during conversation. We use it to maintain relevant information, to inhibit or ignore irrelevant information, and to attend to conversation selectively. Working memory helps us to keep track of and actively participate in conversation, including taking turns and following the gist. This paper examines the Ease of Language Understanding model (i.e., the ELU model, Rönnberg, 2003; Rönnberg et al., 2008) in light of new behavioral and neural findings concerning the role of working memory capacity (WMC) in uni-modal and bimodal language processing. The new ELU model is a meaning prediction system that depends on phonological and semantic interactions in rapid implicit and slower explicit processing mechanisms that both depend on WMC albeit in different ways. It is based on findings that address the relationship between WMC and (a) early attention processes in listening to speech, (b) signal processing in hearing aids and its effects on short-term memory, (c) inhibition of speech maskers and its effect on episodic long-term memory, (d) the effects of hearing impairment on episodic and semantic long-term memory, and finally, (e) listening effort. New predictions and clinical implications are outlined. Comparisons with other WMC and speech perception models are made.
ObservationalLeading journalWikiModerate
The Coronavirus Health and Impact Survey (CRISIS) reveals reproducible correlates of pandemic-related mood states across the Atlantic
Aki Nikolaidis, Diana Paksarian, Lindsay Alexander +10 more · Scientific Reports · 2021 · 260 citations
This observational study found that pre-existing mood, perceived COVID-19 risk, and lifestyle changes (especially disrupted routines and reduced physical activity) consistently predicted negative mood during the pandemic across both US and UK adult samples, with the strongest single predictor being a person's mood before the pandemic began — meaning that for anyone running a self-experiment on mood, tracking your baseline emotional state and daily routine disruptions is more informative than focusing on external pandemic news alone.
Read the breakdown →ObservationalModerate
Identifying Objective Physiological Markers and Modifiable Behaviors for Self-Reported Stress and Mental Health Status Using Wearable Sensors and Mobile Phones: Observational Study
Akane Sano, Sara Taylor, Andrew W. McHill +4 more · Journal of Medical Internet Research · 2018 · 342 citations
BACKGROUND: Wearable and mobile devices that capture multimodal data have the potential to identify risk factors for high stress and poor mental health and to provide information to improve health and well-being. OBJECTIVE: We developed new tools that provide objective physiological and behavioral measures using wearable sensors and mobile phones, together with methods that improve their data integrity. The aim of this study was to examine, using machine learning, how accurately these measures could identify conditions of self-reported high stress and poor mental health and which of the underlying modalities and measures were most accurate in identifying those conditions. METHODS: We designed and conducted the 1-month SNAPSHOT study that investigated how daily behaviors and social networks influence self-reported stress, mood, and other health or well-being-related factors. We collected over 145,000 hours of data from 201 college students (age: 18-25 years, male:female=1.8:1) at one university, all recruited within self-identified social groups. Each student filled out standardized pre- and postquestionnaires on stress and mental health; during the month, each student completed twice-daily electronic diaries (e-diaries), wore two wrist-based sensors that recorded continuous physical activity and autonomic physiology, and installed an app on their mobile phone that recorded phone usage and geolocation patterns. We developed tools to make data collection more efficient, including data-check systems for sensor and mobile phone data and an e-diary administrative module for study investigators to locate possible errors in the e-diaries and communicate with participants to correct their entries promptly, which reduced the time taken to clean e-diary data by 69%. We constructed features and applied machine learning to the multimodal data to identify factors associated with self-reported poststudy stress and mental health, including behaviors that can be possibly modified by the individual to improve these measures. RESULTS: We identified the physiological sensor, phone, mobility, and modifiable behavior features that were best predictors for stress and mental health classification. In general, wearable sensor features showed better classification performance than mobile phone or modifiable behavior features. Wearable sensor features, including skin conductance and temperature, reached 78.3% (148/189) accuracy for classifying students into high or low stress groups and 87% (41/47) accuracy for classifying high or low mental health groups. Modifiable behavior features, including number of naps, studying duration, calls, mobility patterns, and phone-screen-on time, reached 73.5% (139/189) accuracy for stress classification and 79% (37/47) accuracy for mental health classification. CONCLUSIONS: New semiautomated tools improved the efficiency of long-term ambulatory data collection from wearable and mobile devices. Applying machine learning to the resulting data revealed a set of both objective features and modifiable behavioral features that could classify self-reported high or low stress and mental health groups in a college student population better than previous studies and showed new insights into digital phenotyping.
StudyModerate
The “online brain”: how the Internet may be changing our cognition
Joseph Firth, John Torous, Brendon Stubbs +8 more · World Psychiatry · 2019 · 615 citations
The impact of the Internet across multiple aspects of modern society is clear. However, the influence that it may have on our brain structure and functioning remains a central topic of investigation. Here we draw on recent psychological, psychiatric and neuroimaging findings to examine several key hypotheses on how the Internet may be changing our cognition. Specifically, we explore how unique features of the online world may be influencing: a) attentional capacities, as the constantly evolving stream of online information encourages our divided attention across multiple media sources, at the expense of sustained concentration; b) memory processes, as this vast and ubiquitous source of online information begins to shift the way we retrieve, store, and even value knowledge; and c) social cognition, as the ability for online social settings to resemble and evoke real-world social processes creates a new interplay between the Internet and our social lives, including our self-concepts and self-esteem. Overall, the available evidence indicates that the Internet can produce both acute and sustained alterations in each of these areas of cognition, which may be reflected in changes in the brain. However, an emerging priority for future research is to determine the effects of extensive online media usage on cognitive development in youth, and examine how this may differ from cognitive outcomes and brain impact of uses of Internet in the elderly. We conclude by proposing how Internet research could be integrated into broader research settings to study how this unprecedented new facet of society can affect our cognition and the brain across the life course.
StudyLeading journalModerate
Automatic Sleep/Wake Identification From Wrist Activity
Roger J. Cole, Daniel F. Kripke, William Gruen +2 more · SLEEP · 1992 · 1,923 citations
The purpose of this study was to develop and validate automatic scoring methods to distinguish sleep from wakefulness based on wrist activity. Forty-one subjects (18 normals and 23 with sleep or psychiatric disorders) wore a wrist actigraph during overnight polysomnography. In a randomly selected subsample of 20 subjects, candidate sleep/wake prediction algorithms were iteratively optimized against standard sleep/wake scores. The optimal algorithms obtained for various data collection epoch lengths were then prospectively tested on the remaining 21 subjects. The final algorithms correctly distinguished sleep from wakefulness approximately 88% of the time. Actigraphic sleep percentage and sleep latency estimates correlated 0.82 and 0.90, respectively, with corresponding parameters scored from the polysomnogram (p < 0.0001). Automatic scoring of wrist activity provides valuable information about sleep and wakefulness that could be useful in both clinical and research applications.
StudyWikiModerate
Quarantine during COVID-19 outbreak: Changes in diet and physical activity increase the risk of cardiovascular disease
Anna Vittoria Mattioli, Susanna Sciomer, Camilla Cocchi +2 more · Nutrition Metabolism and Cardiovascular Diseases · 2020 · 544 citations
This commentary synthesises evidence that COVID-19 quarantine caused measurable shifts toward unhealthy diets (reduced fruit/vegetable intake, increased processed foods) and decreased physical activity, which collectively increase cardiovascular disease risk — and provides a framework for running your own experiment to reverse these effects.
Read the breakdown →StudyWikiModerate
Recommendations for daytime, evening, and nighttime indoor light exposure to best support physiology, sleep, and wakefulness in healthy adults
Timothy M. Brown, George C. Brainard, Christian Cajochen +15 more · PLoS Biology · 2022 · 538 citations
This expert consensus report provides specific, measurable light exposure targets (in melanopic equivalent daylight illuminance, or melanopic EDI) for daytime, evening, and nighttime to optimise circadian rhythms, sleep quality, and daytime alertness, based on a systematic review of the underlying photobiology.
Read the breakdown →ObservationalModerate
Depression, anxiety and stress in dental students
Sumaya Basudan, Najla Binanzan, Aseel Khaled Alhassan · International Journal of Medical Education · 2017 · 355 citations
OBJECTIVES: To measure the occurrence and levels of depression, anxiety and stress in undergraduate dental students using the Depression, Anxiety and Stress Scale (DASS-21). METHODS: This cross-sectional study was conducted in November and December of 2014. A total of 289 dental students were invited to participate, and 277 responded, resulting in a response rate of 96%. The final sample included 247 participants. Eligible participants were surveyed via a self-reported questionnaire that included the validated DASS-21 scale as the assessment tool and questions about demographic characteristics and methods for managing stress. RESULTS: Abnormal levels of depression, anxiety and stress were identified in 55.9%, 66.8% and 54.7% of the study participants, respectively. A multiple linear regression analysis revealed multiple predictors: gender (for anxiety b=-3.589, p=.016 and stress b=-4.099, p=.008), satisfaction with faculty relationships (for depression b=-2.318, p=.007; anxiety b=-2.213, p=.004; and stress b=-2.854, p<.001), satisfaction with peer relationships (for depression b=-3.527, p<.001; anxiety b=-2.213, p=.004; and stress b=-2.854, p<.001), and dentistry as the first choice for field of study (for stress b=-2.648, p=.045). The standardized coefficients demonstrated the relationship and strength of the predictors for each subscale. To cope with stress, students engaged in various activities such as reading, watching television and seeking emotional support from others. CONCLUSIONS: The high occurrence of depression, anxiety and stress among dental students highlights the importance of providing support programs and implementing preventive measures to help students, particularly those who are most susceptible to higher levels of these psychological conditions.
StudyModerate
An open resource for transdiagnostic research in pediatric mental health and learning disorders
Lindsay Alexander, Jasmine Escalera, Lei Ai +64 more · Scientific Data · 2017 · 705 citations
Technological and methodological innovations are equipping researchers with unprecedented capabilities for detecting and characterizing pathologic processes in the developing human brain. As a result, ambitions to achieve clinically useful tools to assist in the diagnosis and management of mental health and learning disorders are gaining momentum. To this end, it is critical to accrue large-scale multimodal datasets that capture a broad range of commonly encountered clinical psychopathology. The Child Mind Institute has launched the Healthy Brain Network (HBN), an ongoing initiative focused on creating and sharing a biobank of data from 10,000 New York area participants (ages 5-21). The HBN Biobank houses data about psychiatric, behavioral, cognitive, and lifestyle phenotypes, as well as multimodal brain imaging (resting and naturalistic viewing fMRI, diffusion MRI, morphometric MRI), electroencephalography, eye-tracking, voice and video recordings, genetics and actigraphy. Here, we present the rationale, design and implementation of HBN protocols. We describe the first data release (n=664) and the potential of the biobank to advance related areas (e.g., biophysical modeling, voice analysis).
StudyModerate
Student engagement and achievement in American secondary schools
<vcard>BEGIN:vCard\VERSION:3.0\FN:B. Bradford Brown\ORG:University of Wisconsin-Madison\ADR;TYPE=WORK,POSTAL,PARCEL:;;1000 Bascom Mall;Suite 377;Madison;WI;53706;US\END:vCard</vcard>, <vcard>BEGIN:vCard\VERSION:3.0\FN:Adam Gamoran\ORG:University of Wisconsin-Madison\ADR;TYPE=WORK,POSTAL,PARCEL:;;1025 W. Johnson St.;;Madison;WI;53706;US\END:vCard</vcard>, <vcard>BEGIN:vCard\VERSION:3.0\FN:Susie D. Lamborn\ORG:University of Wisconsin-Madison\ADR;TYPE=WORK,POSTAL,PARCEL:;;1000 Bascom Mall;Suite 377;Madison;WI;53706;US\END:vCard</vcard> +7 more · Choice Reviews Online · 1993 · 1,118 citations
Findings from five main projects in the National Center on Effective Secondary Schools, which operated from December 1, 1985 to February 28, 1991, are presented. Projects investigated different aspects of engagement and achievement problems through literature reviews, analyses of existing data sets, and new studies of students and staff in 32 middle and 62 high schools throughout the United States. Material from the projects is integrated into the following chapters: (1) "The Significance and Sources of Student Engagement" (F. M. Newmann, G. G. Wehlage, and S. D. Lamborn); (2) "Taking Students Seriously" (A. Gamoran and M. Nystrand); (3) "Higher-Order Thinking and Prospects for Classroom Thoughtfulness" (F. M. Newmann); (4) "Building New Programs for Students at Risk" (G. G. Wehlage and G. A. Smith); (5) "Cultivating Teacher Engagement: Breaking the Iron Law of Social Class" (K. S. Louis and B. Smith); (6) "Putting School in
StudyModerate
The SEMAINE Database: Annotated Multimodal Records of Emotionally Colored Conversations between a Person and a Limited Agent
Gary McKeown, Michel Valstar, Roddy Cowie +2 more · IEEE Transactions on Affective Computing · 2011 · 667 citations
SEMAINE has created a large audiovisual database as a part of an iterative approach to building Sensitive Artificial Listener (SAL) agents that can engage a person in a sustained, emotionally colored conversation. Data used to build the agents came from interactions between users and an "operator” simulating a SAL agent, in different configurations: Solid SAL (designed so that operators displayed an appropriate nonverbal behavior) and Semi-automatic SAL (designed so that users' experience approximated interacting with a machine). We then recorded user interactions with the developed system, Automatic SAL, comparing the most communicatively competent version to versions with reduced nonverbal skills. High quality recording was provided by five high-resolution, high-framerate cameras, and four microphones, recorded synchronously. Recordings total 150 participants, for a total of 959 conversations with individual SAL characters, lasting approximately 5 minutes each. Solid SAL recordings are transcribed and extensively annotated: 6-8 raters per clip traced five affective dimensions and 27 associated categories. Other scenarios are labeled on the same pattern, but less fully. Additional information includes FACS annotation on selected extracts, identification of laughs, nods, and shakes, and measures of user engagement with the automatic system. The material is available through a web-accessible database.
StudyModerate
Effects of light on human circadian rhythms, sleep and mood
Christine Blume, Corrado Garbazza, Manuel Spitschan · Somnologie - Schlafforschung und Schlafmedizin · 2019 · 626 citations
Humans live in a 24-hour environment, in which light and darkness follow a diurnal pattern. Our circadian pacemaker, the suprachiasmatic nuclei (SCN) in the hypothalamus, is entrained to the 24-hour solar day via a pathway from the retina and synchronises our internal biological rhythms. Rhythmic variations in ambient illumination impact behaviours such as rest during sleep and activity during wakefulness as well as their underlying biological processes. Rather recently, the availability of artificial light has substantially changed the light environment, especially during evening and night hours. This may increase the risk of developing circadian rhythm sleep-wake disorders (CRSWD), which are often caused by a misalignment of endogenous circadian rhythms and external light-dark cycles. While the exact relationship between the availability of artificial light and CRSWD remains to be established, nocturnal light has been shown to alter circadian rhythms and sleep in humans. On the other hand, light can also be used as an effective and noninvasive therapeutic option with little to no side effects, to improve sleep,mood and general well-being. This article reviews our current state of knowledge regarding the effects of light on circadian rhythms, sleep, and mood.
StudyLeading journalModerate
Enhancing Our Lives with Immersive Virtual Reality
Mel Slater, María V. Sánchez-Vives · Frontiers in Robotics and AI · 2016 · 1,755 citations
Virtual reality (VR) started about 50 years ago in a form we would recognize today [stereo head-mounted display (HMD), head tracking, computer graphics generated images] – although the hardware was completely different. In the 1980s and 1990s, VR emerged again based on a different generation of hardware (e.g., CRT displays rather than vector refresh, electromagnetic tracking instead of mechanical). This reached the attention of the public, and VR was hailed by many engineers, scientists, celebrities, and business people as the beginning of a new era, when VR would soon change the world for the better. Then, VR disappeared from public view and was rumored to be “dead.” In the intervening 25 years a huge amount of research has nevertheless been carried out across a vast range of applications – from medicine to business, from psychotherapy to industry, from sports to travel. Scientists, engineers, and people working in industry carried on with their research and applications using and exploring different forms of VR, not knowing that actually the topic had already passed away. \n \nThe purpose of this article is to survey a range of VR applications where there is some evidence for, or at least debate about, its utility, mainly based on publications in peer-reviewed journals. Of course not every type of application has been covered, nor every scientific paper (about 186,000 papers in Google Scholar): in particular, in this review we have not covered applications in psychological or medical rehabilitation. The objective is that the reader becomes aware of what has been accomplished in VR, where the evidence is weaker or stronger, and what can be done. We start in Section 1 with an outline of what VR is and the major conceptual framework used to understand what happens when people experience it – the concept of “presence.” In Section 2, we review some areas where VR has been used in science – mostly psychology and neuroscience, the area of scientific visualization, and some remarks about its use in education and surgical training. In Section 3, we discuss how VR has been used in sports and exercise. In Section 4, we survey applications in social psychology and related areas – how VR has been used to throw light on some social phenomena, and how it can be used to tackle experimentally areas that cannot be studied experimentally in real life. We conclude with how it has been used in the preservation of and access to cultural heritage. In Section 5, we present the domain of moral behavior, including an example of how it might be used to train professionals such as medical doctors when confronting serious dilemmas with patients. In Section 6, we consider how VR has been and might be used in various aspects of travel, collaboration, and industry. In Section 7, we consider mainly the use of VR in news presentation and also discuss different types of VR. In the concluding Section 8, we briefly consider new ideas that have recently emerged – an impossible task since during the short time we have written this page even newer ideas have emerged! And, we conclude with some general considerations and speculations. \n \nThroughout and wherever possible we have stressed novel applications and approaches and how the real power of VR is not necessarily to produce a faithful reproduction of “reality” but rather that it offers the possibility to step outside of the normal bounds of reality and realize goals in a totally new and unexpected way. We hope that our article will provoke readers to think as paradigm changers, and advance VR to realize different worlds that might have a positive impact on the lives of millions of people worldwide, and maybe even help a little in saving the planet.
ObservationalModerate
Health promoting lifestyle of university students in Saudi Arabia: a cross-sectional assessment
Khalid M. Almutairi, Wadi B. Alonazi, Jason M. Vinluan +8 more · BMC Public Health · 2018 · 226 citations
BACKGROUND: College is a critical time where students are more prone to engage in risky health behaviors known to negatively affect well-being, such as physical inactivity, stress, and poor dietary habits. A health promoting lifestyle is an important determinant of health status and is recognized as a major factor for the maintenance and improvement of health. This study was designed to assess the health-promoting lifestyle of students in health colleges and non-health colleges in Saudi Arabia. METHODS: A total of 1656 students participated in this descriptive cross-sectional study. Data gathering was conducted from November 2016 to February 2017 at King Saud University. Participating students completed a self-reported questionnaire that included questions regarding their demographic characteristics and their health-promoting behaviors. RESULTS: The majority of participants were females (70.4%), 20% of the participants were overweight and 11.3%, were obese. The analysis showed that there was a significant difference between health colleges and non-health colleges with regards to the factor of health responsibility. Students at both schools were found to have an inadequate level of adherence to recommendations regarding physical activity and healthy eating habits. The analysis also found that majority of the students in both colleges do not attend educational programs on health care. The model shows that gender, type of college, year in school, and family structure were significant predictors of the health lifestyle of students in Saudi Arabia. CONCLUSION: The results of the current study indicate that university students are leading unhealthy lives, where the majority of them have unhealthy eating habits and poor physical activity level. Universities are ideal settings for implementing health promotion programs. Therefore, planning and implementing programs to motivate students to be more responsible for their own health, to engage more in physical activity, and to practice healthy eating habits and other forms of wellness are of paramount importance.
ObservationalWikiModerate
Longitudinal relationships among problematic mobile phone use, bedtime procrastination, sleep quality and depressive symptoms in Chinese college students: a cross-lagged panel analysis
Guanghui Cui, Yongtian Yin, Shaojie Li +4 more · BMC Psychiatry · 2021 · 159 citations
Problematic mobile phone use and bedtime procrastination mutually reinforce each other over a year, and both independently worsen sleep quality and depressive symptoms—meaning that cutting phone use before bed may break a vicious cycle that degrades both sleep and mood.
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The PERMA-Profiler: A brief multidimensional measure of flourishing
J. Corey Butler, Margaret L. Kern · International Journal of Wellbeing · 2016 · 1,372 citations
In the book Flourish (2011), Seligman defined wellbeing in terms of five pillars: Positive emotion, Engagement, Relationships, Meaning, and Accomplishment, or PERMA. We developed the PERMA-Profiler as a brief measure of PERMA. We first compiled hundreds of theoretically relevant items. Three studies (N = 7,188) reduced, tested, and refined items, resulting in a final set of 15 questions (three items per PERMA domain). Eight additional filler items were added, which assess overall wellbeing, negative emotion, loneliness, and physical health, resulting in a final 23item measure. A series of eight additional studies (N = 31,966) were conducted to test the psychometrics of the measure. The PERMA-Profiler demonstrates acceptable model fit, internal and cross-time consistency, and evidence for content, convergent, and divergent validity. Scores are reported visually as a profile across domains, reflecting the multidimensional nature of flourishing. The PERMA-Profiler adds to the toolbox of wellbeing measures, allowing individuals to monitor their wellbeing across multiple psychosocial domains.
StudyTop journalModerate
High sensitivity and interindividual variability in the response of the human circadian system to evening light
Andrew J. K. Phillips, Parisa Vidafar, Angus C. Burns +5 more · Proceedings of the National Academy of Sciences · 2019 · 417 citations
Significance Electric lighting has fundamentally altered how the human circadian clock synchronizes to the day/night cycle. Exposure to light after dusk is pervasive in the modern world. We examined group-level sensitivity of the circadian system to evening light and the degree to which sensitivity varies between individuals. We found that, on average, humans are highly sensitive to evening light. Specifically, 50% suppression of melatonin occurred at <30 lux, which is comparable to or lower than typical indoor lighting used at night, as well as light produced by electronic devices. Significantly, there was a >50-fold difference in sensitivity to evening light across individuals. Interindividual differences in light sensitivity may explain differential vulnerability to circadian disruption and subsequent impact on human health.